Important safety information including dosage, side effects, and precautions of Oseltamivir.
Dosage & Administration
・(For flu prevention) Adults and children weighing 37.5 kg or more should take 1 tablet once daily.
・If you miss a dose, take it as soon as possible. If it’s almost time for your next dose, skip the missed one and continue your regular schedule.
・Do not take two doses at the same time.
Side Effects
The most commonly reported side effects include rash, diarrhea, abdominal pain, nausea, vomiting, dizziness, headache, insomnia and low body temperature. If any of these symptoms occur, consult with your doctor or pharmacist.
Serious Side Effects
If you develop any of the serious side effects listed below, discontinue use and visit a medical facility immediately:
・Hives, facial/pharyngeal edema, respiratory distress [shock, anaphylaxis]
・General malaise, loss of appetite, yellow discoloration of the skin and the white of eyes [fulminant hepatitis, liver dysfunction, jaundice]
・Fever, redness and swelling of skin/mucosa with rash or blisters, conjunctival hyperemia [mucocutaneous ocular syndrome, toxic epidermal necrolysis]
・Decreased urine output, edema, headache [acute renal disorder]
・Consciousness disorder, delirium, sudden running/wandering [psychiatric/neurological symptoms, abnormal behavior]
Consult with your doctor or pharmacist if you notice any symptoms of concern other than those listed above.
Precautions
・Do not take this medication if you have kidney dysfunction, are pregnant or breastfeeding, and do not give to children under 1 year old.
・Keep out of the reach of children. Store away from direct sunlight, heat and moisture.
Approval status in Japan
・In Japan, Oseltamivir (Tamiflu) is an approved antiviral medication for the treatment and prevention of influenza A and B.
*Medicines prescribed in this department are not covered by the Adverse Reactions Relief System.
Availability of approved medicines that have the same active ingredients in Japan
・In Japan, oral medicines containing the same active ingredient, such as Tamiflu and its generics, are approved for the treatment and prevention of influenza.
Means of acquisition
・Our affiliated clinic physicians purchase Pantogar through a domestic pharmaceutical distributor.
Information on safety and approval in other countries
・In patients under 18 years of age, there have been reports of abnormal behavior, including incidents such as falls, after taking this medication, although a causal relationship has not been established. For this age group, please avoid using this medication in principle unless the patient is considered high risk due to complications or medical history.