ProFeme 10
ProFeme 10% is a cream that replenishes the female hormone progesterone, a hormone that is naturally secreted from the human ovaries. It can also help those experiencing irregular menstrual cycles or seeking pregnancy stabilization.
ProFeme 10 is a hormone cream made in Australia by Lawley Pharmaceuticals. It contains 10% natural progesterone (the same hormone your body produces) and is designed to restore hormonal balance during perimenopause and menopause.
Unlike pills, ProFeme 10 is applied to the skin, where the hormone is absorbed directly into the bloodstream. This makes it a simple and effective way to support your body without putting extra stress on the liver or digestive system.
It’s often prescribed as part of hormone replacement therapy (HRT) to help ease symptoms such as:
- Hot flashes and night sweat
- Mood swings and sleep problems
- Irregular bleeding
- Hormonal imbalance when using estrogen
Regular use can help you feel more balanced both mentally and physically, improve sleep and mood, and support overall health.
ProFeme 10 may be suitable for:
- Women going through perimenopause or menopause.
- Women who need progesterone support while on estrogen therapy.
- Those experiencing hormonal imbalance or progesterone deficiency.
- Individuals looking for a non-oral hormone therapy option.
- Always use this product under the guidance of a qualified healthcare provider.
Do not use ProFeme 10 if you:
- Have severe liver disease (such as cholestatic jaundice, Rotor syndrome, or Dubin–Johnson syndrome).
- Have unexplained abnormal vaginal bleeding.
- Have a history of herpes during pregnancy.
- Have experienced jaundice during pregnancy.
- Have a known allergy or sensitivity to ProFeme® or any of its ingredients.
- Are taking thyroid supplements.
Apply to the inner upper arm, upper thigh, abdomen, chest, or neck.
Please follow the instructions below according to your individual condition and the symptoms you wish to improve.
- For postmenopausal women: Apply 0.3 ml of cream (30 mg of progesterone) once daily or in divided doses. Use for 25 days per month or 3 weeks, followed by a 1-week drug holiday.
- For perimenopausal women: Apply 0.3 ml of cream (30 mg of progesterone) once daily or in divided doses with a metered applicator on days 12-26 of each menstrual cycle. If menstruation begins before the 26th day, discontinue use of ProFeme® and consider the first day of bleeding as the first day of the new menstrual cycle.
- For premenstrual syndrome (PMS): Apply 0.3 ml of cream (30 mg of progesterone) once daily or in divided doses with a metered applicator on days 12-26 of the menstrual cycle. This dosage can be significantly adjusted 4-5 days prior to menstruation to achieve a crescendo effect.
- For premenstrual dysphoric disorder (PMDD): Apply 0.5-1.0 ml of cream (50-100 mg of progesterone) once daily or in divided doses with a metered applicator on days 12-26 of each menstrual cycle. This dosage can be significantly adjusted to peak 4-5 days prior to menstruation.
- For endometriosis, menstrual pain, and postpartum depression: Apply 1.0-2.0 ml of cream (100-200 mg of progesterone) once daily or in divided doses depending on the severity of symptoms. For women with a reproductive cycle, start treatment on days 12-26, but the frequency can be increased up to 3 times in 4 weeks if symptoms or pain reappear during the drug holiday.
- For infertility/recurrent first-trimester miscarriage (Luteal phase and first trimester pregnancy support): Apply 1 ml of cream (100 mg of progesterone) once daily or in divided doses with a metered applicator on days 12-26 of each cycle until pregnancy is confirmed, and then continue applying 1-2 ml daily until at least the 13th week or until term.
Why people choose ProFeme 10
Better results with cream applications
With oral medications, the liver breaks them down before absorption, reducing effectiveness. Creams applied to blood-rich areas like inner arms or thighs absorb directly, improving results.
Made with natural hormones
The progesterone contained in ProFeme 10 is identical to the hormone naturally produced by the human body, ensuring safe use.
Easy-to-use application
Unlike injectables or oral medications, simply apply once daily on the inner arms or upper thighs. (depends on the doctor’s instruction.)
Menopause Relief Plan
- Estriel 1mg (90 pills)
- ProFeme 10% Cream (1 bottle)
To help reduce the risk of endometrial disorders that can occur when taking oral estrogen alone, it is recommended to use progesterone cream together as part of treatment.
What is progesterone?
There are two types of female hormones: estrogen and progesterone.
In your 30s, the production of female hormones gradually decreases. Progesterone tends to decline earlier than estrogen. If estrogen remains higher than progesterone for an extended period, it can increase the risk of breast cancer, uterine cancer, and uterine fibroids.
Menopausal symptoms arise due to this decline in female hormones.
*Data from clinical trials studying Semaglutide (Ozempic, Rybelsus generic) and Tirzepatide (Mounjaro generic) in patients without diabetes with a BMI ≥30 or BMI ≥27. Semaglutide resulted in an average weight loss of 15% over 68 weeks, according to the New England Journal of Medicine (NEJM) study. In comparison, Tirzepatide led to an average weight loss of 22.5% over 72 weeks, as reported in the SURMOUNT-1 study.
Progesterone benefits for HRT
Hot flashes, flushing, and sweating:
Alleviates vasomotor symptoms for a more comfortable daily life.
Improved sleep:
Helps you fall asleep more easily and supports deep, high-quality rest.
Mental stability:
Eases mood swings and irritability, promoting emotional balance.
Prevention of osteoporosis:
Helps prevent loss of bone density and supports a healthy body.
How to take
The usage of progesterone cream varies depending on your symptoms and treatment goals.
In general, it is applied to areas such as the inner upper arms, upper thighs, abdomen, chest, or neck.
Please read more below for detailed usage guidelines.
Possible side effects
The following side effects may occur. While these side effects usually disappear with dose adjustment, please consult your doctor if you experience any abnormalities.
- Breast pain or tenderness
- Slight vaginal bleeding
- Dizziness, nausea, fatigue, headache, mild headache
Please note that ProFeme contains the same hormone secreted by the human ovary, so side effects are usually minimal.
How it works
Book online
Create an account, answer a short medical questionnaire, and talk directly to a counselor, or book an appointment.
Consult a doctor
After a one-on-one counseling session, the doctor will provide an online consultation via smartphone.
Receive your medication
Discreet packaging, delivered the next day right to your doorstep.*
Related treatments
Why choose elife?
Free online consultation
One-on-one consultation with bilingual counselors / doctors
Same-day shipping
Available depending on the time of your order
Fully online process
From consultation to delivery, all on your smartphone
Frequently asked questions
If you forget to apply your ProFeme 10 cream, missing a single dose will not significantly affect your treatment.
- If you remember within 9 hours of your usual application time, apply the missed dose as soon as possible.
- If more than 9 hours have passed, skip the missed dose and apply the next scheduled dose at the usual time.
*Do not apply extra cream to make up for a missed dose.
- All consultations are free.
Our subscription service is a plan that delivers your medication at regular intervals.
As shown below, only the second payment and shipment will be made on an earlier cycle than the third and subsequent payments and shipments.
*Please note that subscription durations vary between treatment categories. Please check the respective page of each treatment category for more details.
- 10 Day Trial Plan (Rybelsus 3mg, 7mg, Kampo, Pantogar)
The second payment and shipment will be made 8 days after the first payment date, and will be thereafter automatically convert to a monthly subscription plan. The third and subsequent payments and shipments will be made at 30-day intervals from the second payment date.
- Monthly subscription (if the number of pills per month is a multiple of 30)
The second payment and shipment will be made 25 days after the first payment date. The third and subsequent payments and shipments will be made at 30-day intervals from the second payment date.
- Monthly subscription (if the number of pills per month is a multiple of 28, or if the medicine is an injection type)
The second payment and shipment will be made 23 days after the first payment date. The third and subsequent payments and shipments will be made at 28-day intervals from the second payment date.
- 45-day interval Subscriptions (ED)
The second payment and shipment will be made 40 days after the first payment date. The third and subsequent payments and shipments will be made at 45-day intervals from the second payment date.
- 2-month interval Subscriptions (ED)
The second payment and shipment will be made 55 days after the first payment date. The third and subsequent payments and shipments will be made at 60-day intervals from the second payment date.
- 3-month interval Subscriptions (if the number of pills per month is a multiple of 30)
The second payment and shipment will be made 85 days after the first payment date. The third and subsequent payments and shipments will be made at 90-day intervals from the second payment date.
- 3-month interval Subscriptions (if the number of pills per month is a multiple of 28, or if the medicine is an injection type)
The second payment and shipment will be made 79 days after the first payment date. The third and subsequent payments and shipments will be made at 84-day intervals from the second payment date.
- 6-month interval Subscriptions (if the number of pills per month is a multiple of 30)
The second payment and shipment will be made 175 days after the first payment date. The third and subsequent payments and shipments will be made at 180-day intervals from the second payment date.
- 6-month interval Subscriptions (if the number of pills per month is a multiple of 28, or if the medicine is an injection type)
The second payment and shipment will be made 163 days after the first payment date. The third and subsequent payments and shipments will be made at 168-day intervals from the second payment date.
- 12-month interval Subscriptions (Medical Skincare only)
The second payment and shipment will be made 355 days after the first payment date. The third and subsequent payments and shipments will be made at 360-day intervals from the second payment date.
If you are unable to take your medication due to illness or other unavoidable circumstances, please cancel your subscription from your My Page at least two days before the next payment and shipment date.